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ALLERGY PROFILES/COMBINATIONS

What is an allergy?
An allergy is an unpleasant physical reaction that a person experiences when the body is exposed to a substance to which that person is hypersensitive. Such substances, which are harmless to many people, are called allergens. Allergy can affect a wide variety of organs in the body and manifests a range of symptoms.

 

Target Area Common Symptoms
Nose Nasal itching, congestion, sneezing, postnasal drip, watery discharge commonly associated with "hay fever", or allergic rhinitis
Eyes Itching, redness, swelling, tearing and other conjunctivitis symptoms
Ears Fluid in middle ear, recurrent infections
Lungs Asthmatic symptoms such as shortness of breath, wheezing, tightness in the chest, coughing
Skin (including lips, inside of mouth/ears) Itchy welts or "hives" (urticaria) of varying sizes
Skin (contact dermatitis) Blistery rash, intense itching
Skin (eczema) Dry, itchy rash
Digestive Tract Stomach cramps, vomiting, diarrhea (associated with food allergy)
Other possible allergy symptoms include headaches, fatigue, hyperactivity, and depression.

How is allergy diagnosed?
The diagnosis of allergy begins with assessment of the patient's clinical history and symptoms. Allergy testing may then be used to identify the specific causes of the allergic reaction.

Traditionally, a patient was tested for allergy by applying a small quantity of allergen to a puncture in the skin and measuring the reaction that develops. Skin testing is qualitative and highly technique-dependent and may result in some discomfort for the patient.

Now, advanced technology is available that permits the physician to diagnose allergy from a blood sample. The test quantitatively measures immunoglobulin E (IgE) that is specific to the allergens being tested. A single blood sample can provide allergen-specific IgE test results to a variety of allergens, allowing primary care physicians the opportunity for early diagnosis and treatment of allergic patients.

Why is it important to test for allergies?
Diagnostic allergy testing can play an important role in assessing the potential of atopic disease in symptomatic patients. Accurate diagnosis of allergen sensitivity can allow health care providers to develop an optimal therapeutic approach.

Early diagnosis and treatment of the allergic patient has been shown to modify the course of the disease and prevent subsequent development of other conditions such as asthma.  As reported in the Expert Panel Report 2 funded by the National Institutes of Health, atopy, the genetic state of hyperresponsiveness to allergens, is the strongest identifiable predisposing factor for the development of asthma.  It has been hypothesized that allergic sensitization at a young age results in a state of chronic airway inflammation, which increases the child's susceptibility to nasal and ear infections.  Chronic allergy-mediated inflammation and associated infections can cause mucosal damage and lung remodeling that can ultimately lead to asthma.

A number of studies, including one published in the 1999 World Health Organization ARIA Workshop Report, indicate that early treatment of allergy can change the course of disease progression, with clinical intervention appearing the most effective if treatments are initiated before the age of six. This finding emphasizes the importance of early diagnostic testing.


Acid Anhydride Profile

Profile Includes

  Phthalic Anhydride-Specific IgE
  Trimellitic Anhydride-Specific IgE

Hypersensitivity Pneumonitis Profile

Profile Includes

  Aspergillus fumigatus #1 Antibodies
  Aureobasidium pullulans Antibodies
  Micropolyspora faeni Antibodies
  Pigeon Serum Antibodies
  Thermoactinomyces sacchari
  Thermoactinomyces vulgaris #1

Isocyanates Profile

Profile Includes

  Hexamethylene Diisocyanate (HDI)-Specific IgE
  Methylene Diphenyl Diisocyanate (MDI)-Specific IgE
  Toulene Diisocyanate (TDI)-Specific IgE

Multiple Inhalant Allergen (MIA) Test

Profile Includes

  IgE antibodies directed against the major seasonal allergens (grasses, trees, weeds) and the most common perennials

Mini-Allergen Profile

Profile Includes

  Alternaria tenuis
  Bermuda Grass
  Cat Hair (standardized)
  D. farinae (dust mite)
  Dog Epithelia
  Elm
  English Plantain
  Kentucky Bluegrass (June Grass)
  Oak
  Ragweed, Short

Food Profile

Profile Includes

  Beef
  Chocolate
  Corn
  Egg (whole)
  Fish/Shell Mix
  Milk (cow)
  Peanut
  Pork
  Soybean
  Wheat

Mold

Profile Includes

  Alternaria tenuis
  Aspergillus fumigatus
  Candida albicans
  Cladosporium herbarum
  Epicoccum purpurascens
  Fusarium moniliforme
  Helminthosporium sativum
  Hormodendrum hordei
  Mucor racemosus
  Penicillium notatum
  Phoma betae
  Pullularia pullulans
  Stemphylium solani

Seasonal Allergen Profiles

Spring - Tree

Profile Includes

  Alder, Smooth
  Beech
  Birch, White
  Cedar, Mountain
  Elm, American
  Hickory, White
  Maple, Red
  Oak, White
  Poplar
  Sycamore, American
  Walnut
  Willow, Black

Summer - Grass

Profile Includes

  Alternaria tenuis
  Bahia Grass
  Bermuda Grass
  Cladosporium herbarum
  Fescue, Meadow
  Johnson Grass
  Kentucky Bluegrass (June Grass)
  Mucor racemosus
  Rye Grass, Perennial
  Timothy

Fall - Weed

Profile Includes

  Cocklebur
  English Plantain
  Goldenrod
  Kochia (Firebush)
  Lamb's Quarter
  Marsh Elder
  Mugwort
  Pigweed, Rough
  Ragweed, False
  Ragweed, Short
  Wingscale
  Wormwood
  Yellow Dock

Perennial Allergen Profile

Profile Includes

  Alternaria tenuis
  Aspergillus fumigatus
  Candida albicans
  Cat Hair (standardized)
  Chicken Feathers
  Cladosporium herbarum
  Cow Epithelia
  D. farinae (dust mite)
  Dermatophagoides pteronyssinus
  Dog Epithelia
  Duck Feathers
  Goose Feathers
  Helminthosporium sativum
  Mucor racemosus
  Penicillium notatum
  Phoma betae
  Pullularia pullulans
  Stemphylium solani

Regional Allergen Profiles (See Zone Map)

Zone 1

(States: CT, MA, ME, NH, NY, RI, and VT)

Profile Includes

  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Bahia Grass
  Bermuda Grass
  Cat Hair (standardized)
  Cladosporium herbarum
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  English Plantain
  Hazelnut
  Kentucky Bluegrass
  Mucor racemosus
  Mugwort
  Nettle
  Penicillium notatum
  Pigweed, Rough
  Ragweed, Short
  Red Cedar
  Red Maple
  Red Mulberry
  Sheep Sorrel
  Stemphylium botryosum
  White Ash
  White Birch
  White Hickory
  White Oak

Zone 2

(States: DE, MD, NJ; Coastal FL, GA, NC, SC, and VA)

Profile Includes

  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Bahia Grass
  Bermuda Grass
  Cat Hair (standardized)
  Cladosporium herbarum
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  English Plantain
  Johnson Grass
  Mucor racemosus
  Mugwort
  Nettle
  Penicillium notatum
  Pigweed, Rough
  Ragweed, Short
  Red Cedar
  Red Maple
  Red Mulberry
  Sheep Sorrel
  Stemphylium botryosum
  Sweet Gum
  Sycamore
  Timothy
  White Birch
  White Hickory
  White Oak

Zone 3

(States: NC, PA, SC, VA, and WV)

Profile Includes

  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Bahia Grass
  Bermuda Grass
  Cat Hair (standardized)
  Cladosporium herbarum
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  English Plantain
  Johnson Grass
  Kentucky Bluegrass
  Locust
  Mucor racemosus
  Nettle
  Penicillium notatum
  Pigweed, Rough
  Ragweed, Short
  Red Cedar
  Red Maple
  Red Mulberry
  Stemphylium botryosum
  White Birch
  White Hickory
  White Oak

Zone 4

(States: Middle FL)

Profile Includes

  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Baccharis
  Bahia Grass
  Bald Cypress
  Bayberry
  Bermuda Grass
  Cat Hair (standardized)
  Cladosporium herbarum
  Coastal Live Oak
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  Dog Fennel
  English Plantain
  Eucalyptus
  Johnson Grass
  Lamb's Quarter
  Mango
  Mucor racemosus
  Penicillium notatum
  Perennial Rye
  Queen Palm
  Ragweed, Short
  Red Maple
  Red Mulberry
  Sheep Sorrel
  Stemphylium botryosum

Zone 5

(States: Southern FL)

Profile Includes

  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Baccharis
  Bahia Grass
  Bald Cypress
  Bayberry
  Bermuda Grass
  Cat Hair (standardized)
  Cladosporium herbarum
  Coastal Live Oak
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  Dog Fennel
  English Plantain
  Eucalyptus
  Johnson Grass
  Lamb's Quarter
  Mango
  Mucor racemosus
  Penicillium notatum
  Perennial Rye
  Privet
  Queen Palm
  Ragweed, Short
  Red Maple
  Sheep Sorrel
  Stemphylium botryosum

Zone 6

(States: Coastal AL, LA, TX, MS; Northwestern FL; and Southern GA)

Profile Includes

  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Bahia Grass
  Bermuda Grass
  Cat Hair (standardized)
  Cladosporium herbarum
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  English Plantain
  Johnson Grass
  Mucor racemosus
  Mugwort
  Nettle
  Penicillium notatum
  Pigweed, Rough
  Ragweed, Short
  Red Cedar
  Red Maple
  Red Mulberry
  Sheep Sorrel
  Stemphylium botryosum
  Sweet Gum
  Sycamore
  Timothy
  White Hickory
  White Oak

Zone 7

(States: AR, Eastern NM, Northern LA, OK, and TX)

Profile Includes

  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Bahia Grass
  Bermuda Grass
  Box Elder
  Cat Hair (standardized)
  Cladosporium herbarum
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  English Plantain
  Johnson Grass
  Kentucky Bluegrass
  Mesquite
  Mountain Cedar
  Mucor racemosus
  Nettle
  Penicillium notatum
  Pigweed, Rough
  Ragweed, Short
  Sheep Sorrel
  Stemphylium botryosum
  Sweet Gum
  White Ash
  White Hickory
  White Mulberry
  White Oak
  Wingscale

Zone 8

(States: IN, KY, Northern AL, Northern GA, Northern MS, OH, and TN)

Profile Includes

  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Bahia Grass
  Bermuda Grass
  Cat Hair (standardized)
  Cladosporium herbarum
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  English Plantain
  Hazelnut
  Johnson Grass
  Kentucky Bluegrass
  Locust
  Mucor racemosus
  Mugwort
  Nettle
  Penicillium notatum
  Pigweed, Rough
  Ragweed, Short
  Red Cedar
  Red Maple
  Red Mulberry
  Sheep Sorrel
  Stemphylium botryosum
  Sweet Gum
  Sycamore
  White Hickory
  White Oak

Zone 9

(States: MI, MN, and WI)

Profile Includes

  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Bermuda Grass
  Box Elder
  Cat Hair (standardized)
  Cladosporium herbarum
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  English Plantain
  Johnson Grass
  Kentucky Bluegrass
  Mucor racemosus
  Mugwort
  Nettle
  Penicillium notatum
  Pigweed, Rough
  Ragweed, Short
  Red Cedar
  Red Mulberry
  Russian Thistle
  Sheep Sorrel
  Spruce
  Stemphylium botryosum
  Sycamore
  White Hickory
  White Oak

Zone 10

(States: IL, IA, MO, and Southwestern MN)

Profile Includes

  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Bermuda Grass
  Cat Hair (standardized)
  Cladosporium herbarum
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  English Plantain
  Johnson Grass
  Kentucky Bluegrass
  Mucor racemosus
  Nettle
  Penicillium notatum
  Pigweed, Rough
  Ragweed, Short
  Red Cedar
  Red Maple
  Red Mulberry
  Russian Thistle
  Sheep Sorrel
  Stemphylium botryosum
  Sycamore
  White Hickory
  White Oak

Zone 11

(States: Eastern CO, KS, NE, ND, and SD)

Profile Includes

  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Bermuda Grass
  Box Elder
  Cat Hair (standardized)
  Cladosporium herbarum
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  English Plantain
  Johnson Grass
  Kentucky Bluegrass
  Mucor racemosus
  Penicillium notatum
  Pigweed, Rough
  Ragweed, Short
  Red Mulberry
  Russian Thistle
  Sheep Sorrel
  Stemphylium botryosum
  Sycamore
  Walnut
  White Ash
  White Oak
  Wormwood

Zone 12

(States: Eastern MT, Western CO, and WY)

Profile Includes

  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Bermuda Grass
  Box Elder
  Cat Hair (standardized)
  Cladosporium herbarum
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  English Plantain
  Johnson Grass
  Kentucky Bluegrass
  Mucor racemosus
  Penicillium notatum
  Pigweed, Rough
  Ragweed, Short
  Red Mulberry
  Russian Thistle
  Sheep Sorrel
  Stemphylium botryosum
  Sycamore
  Walnut
  White Ash
  White Oak
  Wormwood

Zone 13

(States: Central OR, Eastern WA, Northeastern CA, Northeastern ID, and Western MT)

Profile Includes

  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Bermuda Grass
  Cat Hair (standardized)
  Cladosporium herbarum
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  English Plantain
  Johnson Grass
  Kentucky Bluegrass
  Mountain Cedar
  Mucor racemosus
  Nettle
  Penicillium notatum
  Pigweed, Rough
  Ragweed, Short
  Russian Thistle
  Saltbush
  Sheep Sorrel
  Spruce
  Stemphylium botryosum
  White Oak
  Wormwood

Zone 14

(States: Coastal OR, WA; and Northern CA)

Profile Includes

  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Bermuda Grass
  Box Elder
  Cat Hair (standardized)
  Cladosporium herbarum
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  English Plantain
  Johnson Grass
  Kentucky Bluegrass
  Mucor racemosus
  Nettle
  Penicillium notatum
  Pigweed, Rough
  Ragweed, Short
  Redwood
  Russian Thistle
  Sheep Sorrel
  Stemphylium botryosum
  Walnut
  White Birch
  White Oak

Zone 15

(States: Eastern OR, NV, Southeastern WA, Southern ID, and UT)

Profile Includes

  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Bermuda Grass
  Cat Hair (standardized)
  Cladosporium herbarum
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  English Plantain
  Johnson Grass
  Kentucky Bluegrass
  Mountain Cedar
  Mucor racemosus
  Nettle
  Penicillium notatum
  Pigweed, Rough
  Ragweed, Short
  Spruce
  Stemphylium botryosum
  White Birch
  White Oak
  Wingscale
  Wormwood
  Yellow Dock

Zone 16

(States: AZ, Southeastern CA, Southwestern TX, and Western NM)

Profile Includes

  Acacia
  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Bahia Grass
  Bermuda Grass
  Cat Hair (standardized)
  Cladosporium herbarum
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  English Plantain
  Eucalyptus
  Iodine Bush
  Johnson Grass
  Kentucky Bluegrass
  Mountain Cedar
  Mucor racemosus
  Nettle
  Olive
  Pecan
  Penicillium notatum
  Pigweed, Rough
  Rabbit Bush
  Ragweed, Western
  Sagebrush
  Stemphylium botryosum
  Sycamore
  White Mulberry
  White Oak
  Wingscale

Zone 17

(States: AK)

Profile Includes

  Alternaria tenuis
  American cockroach
  American Elm
  Aspergillus fumigatus
  Cat Hair (standardized)
  Cladosporium herbarum
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  English Plantain
  Hazelnut
  Mucor racemosus
  Penicillium notatum
  Ragweed, Short
  Redwood
  Russian Thistle
  Sagebrush
  Sheep Sorrel
  Stemphylium botryosum
  Timothy
  Walnut
  White Birch
  White Oak

Zone 18

(States: HI)

Profile Includes

  Acacia
  Alternaria tenuis
  American cockroach
  Aspergillus fumigatus
  Bahia Grass
  Bermuda Grass
  Cat Hair (standardized)
  Cladosporium herbarum
  Cockleburr
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  English Plantain
  Eucalyptus
  Kentucky Bluegrass
  Mountain Cedar
  Mucor racemosus
  Olive
  Penicillium notatum
  Pigweed, Rough
  Queen Palm
  Ragweed, Slender
  Saltbush
  Stemphylium botryosum
  White Mulberry

Zone 19

(States: Coastal CA)

Profile Includes

  Acacia
  Alternaria tenuis
  American cockroach
  Aspergillus fumigatus
  Bahia Grass
  Bermuda Grass
  Cat Hair (standardized)
  Cladosporium herbarum
  Dermatophagoides farinae
  Dermatophagoides pteronyssinus
  Dog Epithelia
  Eucalyptus
  Mucor racemosus
  Nettle
  Olive
  Pecan
  Penicillium notatum
  Perennial Rye
  Pigweed, Rough
  Ragweed, Western
  Russian Thistle
  Sagebrush
  Saltbush
  Smooth Broome
  Stemphylium botryosum
  Walnut
  Western Sycamore
  White Birch
  White Mulberry
  White Oak

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